HireDiversity

Spring House, PA, US

IN VIVO RESEARCH SCIENTIST-9206130118

Description

Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting for an In Vivo Research Scientist to be located in Spring House, PA.

Janssen Research & Development, L.L.C. is a fully integrated biopharmaceutical and biotechnology company. As a world leader in the field of biomedicines, Janssen strives to develop innovative treatments to improve the health of people worldwide. At the forefront of monoclonal antibody technology and manufacturing, Janssen Research & Development manufactures products including REMICADE® (infliximab), STELARA™ (ustekinumab) and SIMPONI™ (golimumab) for the treatment of various immunological diseases.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

The In Vivo Research Scientist will join the in vivo group efforts in the characterization and development of biologics that function as immune modulators for the treatment of cancer. S/he will be responsible for independently contributing to the ex vivo and in vivo studies for multiple research programs across the different stages of pre-clinical drug discovery. His/her responsibilities include the design, execution and interpretation of in vivo studies for the validation and characterization of targets or therapeutic agents in the area of tumor immunology. Specifically the candidate will establish and perform in vivo target inhibition, efficacy, mechanism of action, and PD biomarker studies and will evaluate the influence of dose, schedule, and combinations in various cancer models. Previous experience with immune-oncology relevant models including xenografts, syngenic models, primary grafts, orthotopic models, transgenics, and genetically engineered mouse tumor models is highly desirable.

The In Vivo Research Scientist will demonstrate the ability to design, perform, interpret and report complex in vivo preclinical cancer models, primarily with immune-therapeutics. S/he will be proficient in in vivo experimentation, proficient in the analysis and understanding of immune cells and molecules (rodent and human) as well as ex vivo analysis of immune cells by FACS, IHC and ELISA. This individual will have experience in cell/molecular biology: analysis and purification of primary immune cells from murine tissues and human blood. S/he will demonstrate the ability to analyze and present data in professional 'publication ready' format. S/he will demonstrate the ability to manage multiple in vivo and in vitro experiments simultaneously.

The In Vivo Research Scientist will demonstrate the ability to contribute on various projects outside of his/her own, and collaborate with stakeholders from all relevant functions, keep up-to-date in the literature related to his/her field. Act as an expert resource in his/her scientific field and in related disciplines, demonstrate clear and professional verbal and written communication, and have the ability to supervise and guide junior Research Associates.

J2W:LI

Qualifications


A PhD degree with 0-3 years post-doctoral experience in cellular and/or tumor immunology or a closely related field is required. Alternatively, a Bachelors Degree with 12 years experience in tumor immunology or closely related field performing progressively advanced duties beyond a BS Degree OR a Masters Degree with 5-7 years experience in cellular and/or tumor immunology or a closely related field performing progressively advanced duties beyond a MS Degree can be considered. A track record of publications in the field is highly desired. Specifically, experience with in vivo mouse tumor models and ex vivo measurement of immune endpoints is required. Extensive experience with primary immune cells of human and/or rodent origin as well as a comprehensive knowledge of the basics of cellular immunology, as it applies to cancer is highly desired. Intellectually curious and well informed on the latest scientific advances in the field is desired. Demonstrated creativity and novel approaches to solving scientific problems is desired. Excellent interpersonal skills with the ability to interact effectively with people, internally and externally is required. Some management experience is preferred. Detail-oriented, with excellent record-keeping skills is required. Excellent oral and written communication skills are required. Able to effectively present scientific data and concepts to international standards is required. This position is located in Spring House, PA.

BE VITAL in your career; be seen for the talent you bring to your work. Explore opportunities within the Johnson & Johnson Family of Companies.

Primary Location:North America-United States-Pennsylvania-Spring House
Organization: Janssen Research & Development, LLC. (6084)